Simultaneous Estimation of Nebivolol Hydrochloride and Hydrochlorothiazide in Tablets by TLC-Densitometry
نویسندگان
چکیده
منابع مشابه
Simultaneous estimation of amlodipine besylate and nebivolol hydrochloride in pharmaceutical tablets formulation by RP-HPLC using PDA detector
Background: The present work was undertaken with the aim to develop and validate a rapid and consistent RP-HPLC method in which the peaks will be appear with short period of time as per ICH Guidelines. Materials and Methods: The separation was achieved on a a stainless steel analytical column, Eclipse XDB plus C18 column (4.6 X 150 mm; 5 μm) in an isocratic mode. The mobile phase w...
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A simple, selective, rapid, precise and economical reverse phase high pressure liquid chromatographic method has been developed for the simultaneous estimation of nebivolol and hydrochlorthiazide from pharmaceutical formulation. Phenomenex Gemini C(18) (25 cm×4.6 mm i.d., 5 μ) column with a mobile phase consisting of acetonitrile: 50mM ammonium acetate (adjusted to pH 3.5 using orthophosphoric ...
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A new sensitive, simple, rapid, accurate and precise method for simultaneous quantification of nebivolol HCl (NEB) and hydrochlorothiazide (HCT) in combined tablet dosage form has been developed. The method is based on the derivative spectrophotometric method at zero-crossing wavelengths. Two wavelengths 280nm (zero crossing point for NEB) and 272.2nm (zero crossing point for HCT) were selected...
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متن کاملSimultaneous Spectrophotometric Estimation of Imipramine Hydrochloride and Chlordiazepoxide in Tablets
A binary mixture of imipramine HCl and chlordiazepoxide was determined by three different spectrophotometric methods. The first method involved determination of imipramine HCl and chlordiazepoxide using the simultaneous equations and the second method involved absorbance ratio method. Imipramine has absorbance maxima at 251 nm, chlordiazepoxide has absorbance maxima at 264.5 nm and isoabsorptiv...
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ژورنال
عنوان ژورنال: Journal of Chromatography & Separation Techniques
سال: 2012
ISSN: 2157-7064
DOI: 10.4172/2157-7064.1000141